检索结果：
返回 58 结果。
排序：
- 作者：
Wang, Xiuqing ，Zhu, Mingxing ，Yang, Guimao ，Su, Chunxia ，Zhang, Aijun ，Cao, Ruibing ，Chen, Puyan （ aSchool of Clinical Laboratory of Medicine, NingXia Medical University, Yinchuan 750004, China;bLaboratory Animal Centre, NingXia Medical University, Yinchuan 750004, China;cSchool of Basic Medical Science, NingXia Medical University, Yinchuan 750004, China;dKey Laboratory of Animal Disease Diagnosis and Immunology, Ministry of Agriculture, Nanjing Agricultural University, Nanjing 210095, China ） - 出处： Experimental and Therapeutic Medicine 2011 Vol.2 No.4 P655-660
- 关键词： Antibacterial activity Antimicrobial assays Cecropin B Expression Pichia pastoris
- 摘要： Natural cecropin B , consisting of 35 amino acids, is a member of the cecropin family with the highest antibacterial activity. Here, a novel approach
- 作者：
苏春霞 ，段相国 ，侯嘉 ，段婷 ，闫亚娟 - 关键词： 免疫佐剂 重组疫苗 干扰素-α 免疫增强作用 枸杞多糖
- 摘要： 接种疫苗仍然是发展中国家控制口蹄疫的一项重大策略。传统的FMD疫苗对防控FMD起了很重要的作用,但传统疫苗存在生物安全隐患、免疫性较差及免疫期较短等缺点。新型疫苗较传统疫苗安全,但免疫原性弱,因此研制疫苗佐剂来增强免疫应答成为疫苗研究的热点方向。该项目研发的口蹄疫新型疫苗佐剂包括干扰素-α和枸杞多糖
期刊
- 作者：
Jiayu Liu ，Jiao Zhang ，Yongsheng Zhou ，Tianrui Huang ，Ting Wang ，Li Liu ，Zhirong Guan ，Bin Ma ，Chunxia Su ，Xiangguo Duan （ 1College of Inspection, Ningxia Medical University, Yinchuan, Ningxia CN 750000, China;2Department of Pathogen Biology and Immunology, School of Basic Medical Science, Ningxia Medical University, Yinchuan, Ningxia CN 750000, China;3The First School of Clinical Medicine, Department of Oncology Surgery, Ningxia Medical University, Yinchuan, Ningxia CN 750000, China;4Department of Oncology Surgery, The First People’s Hospital of Yinchuan, Yinchuan, Ningxia CN 750000, China ） - 出处： ACS Applied Materials & Interfaces 2026 Vol.18 No.1 P476-500
- 关键词： MVs triple negative breast cancer Faecalibaculum rodentium drug delivery nanodrug
- 摘要： The traditional treatment of triple-negative breast cancer still has limitations. Bacterial membrane vesicles , as a type of natural nanocarrier, hav
期刊
- 作者：
Miao Liu ，Xinjuan Ma ，Ruijie Zhou ，Xiaojuan Yang ，Yongsheng Zhou ，Bin Ma ，Chunxia Su ，Xiangguo Duan （ School of Inspection, Ningxia Medical University, Yinchuan 750004, China. ; School of Inspection, Ningxia Medical University, Yinchuan 750004, China. ; School of Inspection, Ningxia Medical University, Yinchuan 750004, China. ; School of Inspection, Ningxia Medical University, Yinchuan 750004, China. ; The Second School of Clinical Medicine, Ningxia Medical University, Yinchuan 750004, China. ; Department of Oncology Surgery, The First People’s Hospital of Yinchuan, Yinchuan 750004, China. ; School of Basic Medical Sciences, Ningxia Medical University, Yinchuan 750004, China. ; School of Inspection, Ningxia Medical University, Yinchuan 750004, China. ） - 出处： Biomaterials Research 2025 Vol.29
- 摘要： Colorectal cancer remains a major clinical challenge owing to its immunosuppressive tumor microenvironment and limited targeting therapeutic efficien
- 作者：
郭松林 ，刘淼 ，杨小娟 ，段相国 ，苏春霞 （ 1宁夏医科大学总医院医学科学研究院；2宁夏医科大学检验学院；3宁夏医科大学基础医学院 ） - 出处： 重庆医科大学学报 2025 第50卷 第9期 P1218-1227
- 关键词： 替瑞利尤单抗 CD8阳性T细胞 三阴性乳腺癌
- 摘要： 目的：观察T细胞免疫球蛋白和ITIM结构域在三阴性乳腺癌患者肿瘤组织及外周血CD8T细胞的表达，探讨新型TIGIT阻断药物替瑞利尤单抗对TNBC患者外周血CD8T细胞功能的影响。方法：通过癌症基因组图谱数据库、免疫组化染色检测TIGIT在TNBC肿瘤组织的表达，流式细胞术检测TNBC患者外周血CD8
期刊
- 作者：
Chenyang Zhao ，Peng Zhang ，Xiaojuan Yang ，Miao Liu ，Zhirong Guan ，Bin Ma ，Xiangguo Duan ，Chunxia Su （ 1Department of Pathogen Biology and Immunology, School of Basic Medical Science, Ningxia Medical University, China;2Ningxia Key Laboratory of Prevention and Treatment of Common Infectious Diseases of Ningxia Medical University, China;3Chenyang Zhao and Peng Zhang contributed equally to this work.;4School of Inspection, Ningxia Medical University, China;5Department of Oncology Surgery, The First People's Hospital of Yinchuan, China ） - 出处： Free Radical Biology and Medicine 2025 Vol.240 P222-237
- 摘要： Triple-negative breast cancer remains a highly malignant subtype with limited therapeutic options. Here, Epimedokoreanin B , a flavonoid derived from
- 作者：
姜春蕾 ，朱泽琴 ，王凤魁 ，陈建 ，段相国 ，苏春霞 ，池淑红 （ 1宁夏医科大学；2宁夏医科大学总医院风湿免疫科,宁夏医科大学第一临床医学院；3宁夏医科大学总医院核医学科,宁夏医科大学第一临床医学院；4宁夏国龙医院脊柱外科 ） - 出处： 宁夏医科大学学报 2023 第45卷 第12期 P1242-1249
- 关键词： 类风湿关节炎 T细胞免疫球蛋白和黏蛋白结构域3 程序性细胞死亡蛋白1 T细胞免疫球蛋白和ITIM结构域蛋白 DAS28评分
- 摘要： 目的 探讨类风湿关节炎患者外周血中T细胞免疫球蛋白和黏蛋白结构域3、程序性细胞死亡蛋白1及T细胞免疫球蛋白和ITIM结构域蛋白在CD4T和CD8T细胞上的表达情况及其与DAS28评分的相关性。方法 选取2021年3月至2023年4月于宁夏医科大学总医院风湿免疫科确诊为RA患者60例为研究对象，另选取
- 作者：
刘亚楠 ，杨皓凯 ，闫亚娟 ，杨小娟 ，段相国 ，苏春霞 （ 1宁夏医科大学基础医学院；2宁夏医科大学临床医学院 ） - 出处： 中国实验方剂学杂志 2023 第29卷 第11期 P106-112
- 关键词： 枸杞多糖 巨噬细胞RAW264.7 Toll样受体2 Toll样受体4 丝裂原活化蛋白激酶 巨噬细胞半乳糖型凝集素
- 摘要： 目的：探讨枸杞多糖促进巨噬细胞RAW264.7活化的机制。方法：采用不同浓度的LBP刺激巨噬细胞RAW264.7，以100μg·L的脂多糖和100 mg·L半乳糖作为阳性药。LBP刺激24 h后，采用细胞增殖与活性检测试剂盒检测不同给药浓度的LBP对巨噬细胞RAW264.7的毒性影响；采用酶联免疫吸
-
被引量：4
期刊
- 作者：
Xiaojuan Yang ，Qian Cao ，Bin Ma ，Yuhan Xia ，Miao Liu ，Jinhua Tian ，Jian Chen ，Chunxia Su ，Xiangguo Duan （ Affiliations 1 School of Basic Medical Sciences, Ningxia Medical University, Yinchuan, China. 2 College of Clinical Medicine, Ningxia Medical University, Yinchuan, China. 3 Department of Oncology Surgery, The First People's Hospital of Yinchuan, Yinchuan, China. 4 Department of Nutrition, General Hospital of Ningxia Medical University, Yinchuan, China. 5 Guolong Hospital, Yinchuan, China. 6 Department of Pathogen Biology and Immunology, School of Basic Medical Science, Ningxia Medical University, Yinchuan, China. 7 Department of Laboratory Surgery, General Hospital of Ningxia Medical University, Yinchuan, China. ） - 出处： PloS one 2023 Vol.18 No.3 Pe0277155
- 摘要： Based on the relationship between the gut microbiota and colorectal cancer, we developed a new probiotic powder for treatment of colorectal cancer. In
期刊
- 作者：
Jia Hou ，Xia Wang ，Chunxia Su ，Weirong Ma ，Xiwei Zheng ，Xiahui Ge & ，Xiangguo Duan （ Department of Respiratory and Critical Care Medicine, General Hospital of Ningxia Medical University, Ningxia, ChinaJia Hou, Weirong Ma & Xiwei Zheng Ningxia Medical University, Ningxia, ChinaXia Wang Department of Pathogen Biology and Immunology, School of Basic Medical Science, Ningxia Medical University, Ningxia, ChinaChunxia Su Department of Respiratory Medicine, Seventh People’s Hospital of Shanghai University of TCM, Shanghai, ChinaXiahui Ge College of Clinical Medicine, Ningxia Medical University, Ningxia, ChinaXiangguo Duan ） - 出处： Respiratory Research 2022 Vol.23 No.1 P1-14
- 关键词： COPD T-regulatory cells GARP Emphysema MOLT
- 摘要： Background Expression of glycoprotein A dominant repeat has been reported to occur only in activated human naturally occurring regulatory T cells an
- 苏春霞，女，汉族，1977年8月生于宁夏盐池县，农工党，教授，硕士生导师。2007年毕业于南京农业大学大学并获博士学位。研究成果获自治区科技进步奖三等奖1项，宁夏医学科技奖三等奖1项。出版教材4部。发表论文30余篇，获宁夏自然科学优秀学术论文一等奖1项，三等奖1项，获宁夏医学优秀学术论文一等奖1项，二等奖1项。获宁夏医科大学教师授课比赛二等奖1项（团队），三等奖2项。