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期刊
- 作者：
Dan Zhang ，Qianrui Yang ，Huidong Xia ，Qiaohong Jiang ，Jianmin Sun ，Ru Bai （ 1Contributed equally.;2School of Basic Medical Sciences, Ningxia Medical University, Yinchuan, China ） - 出处： Journal of Ethnopharmacology 2026 Vol.363 P121460
- 摘要： Ethnopharmacological relevance Aloperine , an alkaloid derived from Sophora alopecuroides L., demonstrates therapeutic potential against malignant tum
期刊
- 作者：
Liu, Anbu ，Zhang, Shaoting ，Wang, Ming ，Zhang, Liangying ，Xu, Shidong ，Nasimian, Ahmad ，Li, Shujing ，Zhao, Sien ，Cao, Xu ，Tian, Jinhai ，Yu, Yuanyuan ，Fan, Zhaoyang ，Xiao, Kun ，Zhao, Hui ，Kazi, Julhash U. ，Ma, Lijun ，Sun, Jianmin （ 1 NHC Key Laboratory of Metabolic Cardiovascular Diseases Research, Science and Technology Center, School of Basic Medical Sciences Ningxia Medical University Yinchuan China 2 Department of Oncology, School of Medicine, Tongren Hospital Shanghai Jiao Tong University Shanghai China 3 Department of Laboratory Medicine, Division of Translational Cancer Research Lund University Lund Sweden 4 Department of Pediatrics The General Hospital of Ningxia Medical University Yinchuan China 5 Department of Emergency The General Hospital of Ningxia Medical University Yinchuan China 6 Key Laboratory for Regenerative Medicine, School of Biomedical Sciences, Faculty of Medicine, Ministry of Education The Chinese University of Hong Kong Hong Kong SAR China ） - 出处： Molecular Carcinogenesis 2024 Vol.63 No.1 P75-93
- 关键词： DDR GIST imatinib KIT mutation
- 作者：
Ke, Hengning ，Kazi, Julhash U. ，Zhao, Hui ，Sun, Jianmin （ aNingxia Medical University, Department of Pathogen Biology and Immunology, School of Basic Medical Sciences, No. 1160 Shengli Street, Yinchuan, 750004, China;bGeneral Hospital of Ningxia Medical University, Translational Cancer Lab, Yinchuan, China;cLund University, Division of Translational Cancer Research, Lund Stem Cell Center, Department of Laboratory Medicine, Lund, Sweden;dThe Chinese University of Hong Kong, Faculty of Medicine, School of Biomedical Sciences, Sha Tin, Hong Kong, Hong Kong ） - 出处： Cell and Bioscience 2016 Vol.6 No.1
- 关键词： Cancer KIT Signal transduction Targeted therapy
- 摘要： Somatic mutations of KIT are frequently found in mastocytosis and gastrointestinal stromal tumor , while germline mutations of KIT are rare, and only
期刊
- 作者：
Liangying Zhang ，Kun Xiao ，Shaoting Zhang ，Sien Zhao ，Zimei Liu ，Ming Wang ，Kaiyue Qin ，Yuanyuan Yu ，Shujing Li ，Lijun Ma ，Jianmin Sun （ 1School of Basic Medical Sciences, Ningxia Medical University;2Department of Oncology, Tongren Hospital, School of Medicine, Shanghai Jiao Tong University;3The General Hospital of Ningxia Medical University ） - 出处： Scientific Reports 2025 Vol.15 No.1 P1-13
- 关键词： SOCS2 KIT GISTs Mutation Imatinib
- 摘要： The suppressors of cytokine signaling 2 inhibits growth hormone receptor signaling by negative feedback in the regulation of metabolism. In this stu
期刊
- 作者：
Liangying Zhang ，Kun Xiao ，Shaoting Zhang ，Sien Zhao ，Zimei Liu ，Ming Wang ，Kaiyue Qin ，Yuanyuan Yu ，Shujing Li ，Lijun Ma ，null ，Jianmin Sun （ 1School of Basic Medical Sciences, Ningxia Medical University, Shengli Street 1160, Yinchuan, 750004, China;2Department of Oncology, Tongren Hospital, School of Medicine, Shanghai Jiao Tong University, Xianxia Road 1111, Shanghai, 200336, China;3The General Hospital of Ningxia Medical University, Yinchuan, China ） - 出处： Scientific Reports 2025 Vol.15
- 关键词： SOCS2 KIT GISTs Mutation Imatinib
- 摘要： The suppressors of cytokine signaling 2 inhibits growth hormone receptor signaling by negative feedback in the regulation of metabolism. In this stu
期刊
- 作者：
Zhang, Shaoting ，Zhang, Liangying ，Zhang, Dan ，Guo, Yue ，Gao, Yisha ，Jiang, Zongying ，Li, Shujing ，Liu, Anbu ，Cao, Xu ，Tian, Jinhai ，Zhao, Sien ，Yu, Yuanyuan ，Yang, Wei ，Bai, Ru ，Huang, Ling ，Yan, Hongli ，Zhao, Hui ，Sun, Jianmin （ aNHC Key Laboratory of Metabolic Cardiovascular Diseases Research, Science and Technology Center, School of Basic Medical Sciences, Ningxia Medical University, Yinchuan, China;bKey Laboratory for Regenerative Medicine, Ministry of Education, School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong;cDepartment of Pathology, The First Affiliated Hospital of Naval Military Medical University, Shanghai, China;dDepartment of Emergency, The General Hospital of Ningxia Medical University, Yinchuan, China;eDepartment of Gastroenterology, Ningxia Hospital of Integrated Traditional Chinese and Western Medicine, Yinchuan, China;fDepartment of Laboratory Medicine, Changhai Hospital, Naval Military Medical University, Shanghai, China;gKunming Institute of Zoology - The Chinese University of Hong Kong (KIZ-CUHK) Joint Laboratory of Bioresources and Molecular Research of Common Diseases, The Chinese University of Hong Kong, Hong Kong;hHong Kong Branch of CAS Center for Excellence in Animal Evolution and Genetics, The Chinese University of Hong Kong, Hong Kong ） - 出处： Molecular Carcinogenesis 2024 Vol.63 No.7 P1334-1348
- 关键词： FHL2 GIST imatinib KIT mutation
- 摘要： Gastrointestinal stromal tumors are predominately induced by KIT mutants. In this study, we found that four and a half LIM domains 2 was highly expr
会议论文
- 作者：
Anning Yang ，Huiping Zhang ，Jiantuan Xiong ，Jiangyong Sheng ，Songhao Yang ，Mei Deng ，Caiyan Mao ，Jianmin Sun ，Yanhua Wang ，Xiaoling Yang ，Yue Sun ，Haibin Wang ，Yuexia Jia ，Yideng Jiang （ Department of Physiology and Pathophysiology，School of Basic Medical Sciences，Ningxia Medical University，Yinchuan，China；Ningxia Key Laboratory of Vascular Injury and Repair Research，Yinchuan，China；Prenatal Diagnosis Center of Ningxia Medical University General Hospital，Yinchuan，China；Ningxia Key Laboratory of Vascular Injury and Repair Research，Yinchuan，China；Department of Physiology and Pathophysiology，School of Basic Medical Sciences，Ningxia Medical University，Yinchuan，China；Department of Pathogenic Biology and Immunology，School of Basic Medical Sciences，Ningxia Medical University，Yinchuan，China；Division of Translational Cancer Research and Lund Stem Cell Center，Department of Laboratory Medicine，Lund University，Lund，Sweden；Ningxia Key Laboratory of Vascular Injury and Repair Research，Yinchuan，China；Department of anesthesiology，Ningxia Medical University General Hospital，Yinchuan，China ） - 出处： 第十四次全国动脉硬化性疾病学术会议暨第五次中-加动脉粥样硬化及心血管疾病国际研讨会 2017 第十四次全国动脉硬化性疾病学术会议暨第五次中-加动脉粥样硬化及心血管疾病国际研讨会论文集
- 会议录： 第十四次全国动脉硬化性疾病学术会议暨第五次中-加动脉粥样硬化及心血管疾病国际研讨会论文集
- 摘要： Aims: Hyperhomocysteinemiais an independent risk factor of atherosclerosis,miRNAs are involved in atherosclerosis associated inflammation mediated by
- 作者：
张良颖 ，张少婷 ，范朝阳 ，蒋宗英 ，李淑璟 ，刘安步 ，孙建民 （ 宁夏医科大学基础医学院，国家卫生健康委代谢性心血管疾病研究重点实验室，医学科学技术研究中心 ） - 出处： 细胞与分子免疫学杂志 2023 第39卷 第2期 P138-143
- 关键词： KIT D816V 核不均一核糖核蛋白L 核不均一核糖核蛋白K
- 摘要： 目的 探究Ⅲ类酪氨酸激酶受体KIT D816V突变对核不均一核糖核蛋白L和HNRNPK的调控作用.方法 在COS-1非洲绿猴肾细胞表达野生型KIT或KIT D816V,或与HNRNPL或HNRNPK共表达,用免疫沉淀法和Western blot法检测KIT活化及HNRNPL、HNRNPK的磷酸化,通
期刊
- 作者：
LIJUN DU ，KAIKAI DOU ，NIANHAI LIANG ，JIANMIN SUN ，RU BAI （ 1School of Basic Medicine, Ningxia Medical University, Yinchuan, 750004, China 2The Fifth People's Hospital of Ningxia, Shizuishan, 753000, China ） - 出处： Biocell 2023 Vol.47 No.3 P547-554
- 关键词： Aerobic glycolysis microRNA Ovarian cancer
- 摘要： Background: The Warburg effect is considered as a hallmark of various types of cancers, while the regulatory mechanism is poorly understood. Our previ
- 作者：
李淑璟 ，于园园 ，王敏行 ，马金海 ，孙建民 （ 宁夏医科大学基础医学院国家卫生健康委员会代谢性心血管疾病研究重点实验室；宁夏医科大学总医院儿科；宁夏医科大学总医院急诊科 ） - 出处： 宁夏医科大学学报 2022 第8期
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被引量：2
- 孙建民，男，民族，汉，1973年9月生于山东莱西，教授，硕士生导师。2000年毕业于军事医学科学院并获博士学位。发表SCI论文20余篇。