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期刊
- 作者:
Huang, Jie ,Gou, Guojing ,Xue, Bing ,Yan, Qianshun ,Sun, Yue ,Dong, Li-E. ( aDepartment of Chemistry, Ningxia Medical University, Yinchuan 750004, China;bResearch Center of Medical Science and Technology, Ningxia Medical University, Yinchuan 750004, China ) - 出处: International Journal of Pharmaceutics 2013 Vol.450 No.1-2 P323-330
- 关键词: "Dextran-magnetic layered double hydroxide-fluorouracil" delivery system Liposome Magnetic targeted Sustained release
- 摘要: This work was aimed at assessing the preparation and characteristics of 'dextran-magnetic layered double hydroxide-fluorouracil' liposomes . DMFL was
- 作者:
左玲霞 ,权菲芸 ,王佩 ,苟国敬 ( 宁夏医科大学 1基础医学院;临床医学院 ) - 出处: 化学通报(印刷版) 2022 第85卷 第2期 P247-252
- 关键词: 硼 氮 掺杂 二硫化钼 氧还原反应
- 摘要: 对于碱性燃料电池的阴极反应,开发具有优异催化性能的新型催化剂至关重要.本工作采用一种简单的热解方法合成了硼、氮掺杂的二硫化钼材料并将其应用于氧还原电催化分析.通过循环伏安法与线性扫描伏安法等电化学分析方法,采用旋转盘电极与旋转环盘电极等技术测试了该材料的氧还原催化活性.结果 表明,制备的B,N-Mo
期刊
- 作者:
Tian, Zonghua ,Zhao, Yue ,Mai, Yaping ,Qiao, Fangxia ,Guo, Jueshuo ,Dong, Luning ,Niu, Yang ,Gou, Guojing ,Yang, Jianhong ( 1 Department of Pharmaceutics, School of Pharmacy, Ningxia Medical University, Yinchuan, China 2 Department of Medical Science and Technology Research Center Department, Ningxia Medical University, Yinchuan, China 3 Key laboratory of Ningxia Ethnomedicine Modernization, Ministry of Education, Ningxia Medical Ningxia Medical University, Yinchuan, China 4 Department of Medical Chemistry, School of Basic Medicine, Ningxia Medical University, Yinchuan, China ) - 出处: International Journal of Pharmaceutics 2022 Vol.616
- 关键词: Bufadienolides Intestinal absorption Multicomponent Nanocrystals Transcytosis
- 摘要: BU nanocrystals with different stabilizers, which codelivery three kinds of crude anti-tumor active ingredients with synergistic effect, were success
- 作者:
左玲霞 ,权菲芸 ,王佩 ,苟国敬 ( 宁夏医科大学基础医学院;宁夏医科大学临床医学院 ) - 出处: 化学通报 2022 第85卷 第2期 P247-252
- 关键词: 硼 氮 掺杂 二硫化钼 氧还原反应
- 摘要: 对于碱性燃料电池的阴极反应,开发具有优异催化性能的新型催化剂至关重要。本工作采用一种简单的热解方法合成了硼、氮掺杂的二硫化钼材料并将其应用于氧还原电催化分析。通过循环伏安法与线性扫描伏安法等电化学分析方法,采用旋转盘电极与旋转环盘电极等技术测试了该材料的氧还原催化活性。结果表明,制备的B,N-MoS
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被引量:5
期刊
- 作者:
Chunhua Shu ,Rui Wang ,Xiaoke Zhang ,Hongyong Wen ,Zonghua Tian ,Xia Wu ,Jianhong Yang ,Guojing Gou ( Department of Pharmaceutics, College of Pharmacy, Ningxia Medical University ; Department of Pharmacology, Key Laboratory of Ministry of Education in Fertility Preservation and Maintenance, Ningxia Medical University ; Department of Stomatology, People’s Hospital of Longde ; Department of Pharmaceutics, College of Pharmacy, Ningxia Medical University ; Department of Pharmaceutics, College of Pharmacy, Ningxia Medical University ; Department of Pharmaceutics, College of Pharmacy, Ningxia Medical University ; Department of Pharmaceutics, College of Pharmacy, Ningxia Medical University ; Department of Pharmaceutics, College of Pharmacy, Ningxia Medical University Medical Chemistry Department, School of Basic Medical, Ningxia Medical University ) - 出处: Biological and Pharmaceutical Bulletin 2021 Vol.44 No.10 P1473-1483
- 关键词: oncosis lysosomal membrane permeability cathepsin dextran-magnetic layered double hydroxide-fluorouracil
- 摘要: The “dextran-magnetic layered double hydroxide-fluorouracil” drug delivery system is a new type of pharmaceutic preparation that can cause cancer cel
期刊
- 作者:
Shuang Li ,Jueshuo Guo ,Zonghua Tian ,Jing Chen ,Guojing Gou ,Yang Niu ,Li Li ,Jianhong Yang ( 1 Department of Pharmaceutics, School of Pharmacy, Ningxia Medical University, No. 1160 Shengli South Street, 750004, Yinchuan, China; 2 Department of Preparation Center, General Hospital of Ningxia Medical University, Yinchuan, China; 3 Department of Medical Chemistry, School of Basic Medicine, Ningxia Medical University, Yinchuan, China; 4 Key Laboratoryratory of NingXia Ethnomedicine Modernization, Ministry of Education, Ningxia Medical University, Yinchuan, China ) - 出处: AAPS PharmSciTech 2021 Vol.22 No.7
- 关键词: Piperine Transferrin Nanoparticles Antitumor 4T1 breast cancer
- 摘要: The purpose of this study was to enhance the antitumor effect of piperine by constructing the nanoparticles modified with transferrin and evaluating
- 作者:
苟国敬 ,鲍凤娟 ,刘彦红 ( 宁夏医科大学医用化学系 ) - 出处: 化学研究与应用 2012 第24卷 第2期 P192-198
- 关键词: “右旋糖酐-磁性层状复合氢氧化物-氟尿嘧啶”转运模型 5-氟尿嘧啶定量检测 HPLC内标法
- 摘要: 用溴尿嘧啶作内标,制备生物样本、沉降蛋白、酯萃法提取待测组分,建立氟尿嘧啶浓度测定方法,检测“右旋糖酐-磁性层状复合氢氧化物-氟尿嘧啶”给药干预大鼠体内组织中的氟尿嘧啶浓度。结果表明溴尿嘧啶内标HPLC法回收率高、精密度好、结果重现性好、测试稳定性高;在外加磁场和多次给药干预条件下,测得不同实验组动
- 作者:
苟国敬 ,马培华 ( 宁夏医科大学;中国科学院青海盐湖研究所 ) - 出处: 化学研究与应用 2009 第21卷 第4期 P463-467
- 关键词: 层状复合氢氧化物 表面改性 热塑性硫化胶 阻燃作用
- 摘要: 用氩载氨气泡膜限域共沉淀反应合成了层状复合氢氧化物及其硬脂酸改性样品,与热塑性硫化胶Santoprene熔炼制成LDH/Santoprene复合材料,在EDS、XRD、IR和N2吸解表征的基础上,对LDH-Santoprene复合物的机械性能及燃烧性能进行了测试评价。结果表明所用合成方法能够实现小尺
- 作者:
连松刚 ,苟国敬 ,葛文佳 ( 宁夏医学院基础学院 ) - 出处: 化学研究与应用 2008 第20卷 第2期 P177-180
- 关键词: 氢氧化铝 表面改性 溶解度
- 作者:
苟国敬 ,鲍凤娟 ,郑志详 ( 宁夏医学院基础学院 ) - 出处: 化学研究与应用 2008 第20卷 第9期 P1158-1162
- 关键词: 抗肿瘤药物氟尿嘧啶 插层复合物 柱撑模型
- 摘要: MeAl type layered double hydroxide obtained by co - precipitation has been used as precursors to intercalate anantineoplastic agent fluorouracil to p
- 苟国敬,男,汉,1964年1月生于宁夏隆德,中共党员,教授,硕士生导师。2005年毕业于中国科学院研究生院并获理学博士学位,历任医用化学系副主任、化学学科带头人等职。国家“百千万人才工程”第三层次人选。中国发明专利优秀奖获得者;享受国务院政府特殊津贴。成果获自治区科技进步三等奖2项,获国家专利授权10项。出版内部教材1部。发表论文35篇,获宁夏自然科学优秀学术论文一等奖2项、二等奖4项、三等奖3项。