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期刊
- 作者:
Wenjuan Zheng ,Shan Li ,Xinle Zhou ,Yafei Zhu ,Bo Wang ,Jierui Yan ,Xiaobo Wang ,Qihang Ding ,Qipeng Zhao ( 1School of Pharmacy, Key Laboratory of Dryness Syndrome in Chinese Medicine, Key Laboratory of Protection, Development and Utilization of Medicinal Resources in Liupanshan Area, Ministry of Education, School of Nursing, Ningxia Medical University, Yinchuan, 750004, Ningxia, China;2These authors contributed equally as co-first authors.;3Department of Chemistry, Korea University, Seoul, 02841, South Korea;4Ministry of Education Key Laboratory of Combinatorial Biosynthesis and Drug Discovery, School of Pharmaceutical Sciences, Wuhan University, Wuhan, 430071, Hubei, China;5Innovative Institute of Chinese Medicine and Pharmacy/Institute of Interdisciplinary Studies, Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, Sichuan, China ) - 出处: Chemical Engineering Journal 2026 Vol.535 P175657
- 摘要: Ischaemic stroke is driven by dynamic core–penumbra evolution, oxidative stress–inflammation amplification and blood–brain barrier dysfunction, yet c
期刊
- 作者:
Wenjuan Zheng ,Shan Li ,Xinle Zhou ,Yafei Zhu ,Bo Wang ,Jierui Yan ,Xiaobo Wang ,Qihang Ding ,Qipeng Zhao ( 1School of Pharmacy, Key Laboratory of Dryness Syndrome in Chinese Medicine, Key Laboratory of Protection, Development and Utilization of Medicinal Resources in Liupanshan Area, Ministry of Education, School of Nursing, Ningxia Medical University, Yinchuan, 750004, Ningxia, China;2These authors contributed equally as co-first authors.;3Department of Chemistry, Korea University, Seoul, 02841, South Korea;4Ministry of Education Key Laboratory of Combinatorial Biosynthesis and Drug Discovery, School of Pharmaceutical Sciences, Wuhan University, Wuhan, 430071, China;5Innovative Institute of Chinese Medicine and Pharmacy, Institute of Interdisciplinary Studies, Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, Sichuan, China ) - 出处: Chemical Engineering Journal 2026 P175657
- 摘要: Ischaemic stroke is driven by dynamic core–penumbra evolution, oxidative stress–inflammation amplification and blood–brain barrier dysfunction, yet c
- 作者:
Li, Wen-Xi ,Wang, Xiao-Ye ,Li, Zhi-Hui ,Huang, Li-Juan ,Qiang, Ke-Ping ,Zhao, Qi-Peng ,Wang, Yan-Hua ( aThe First Clinical Medical College, Institute of Medical Sciences, General Hospital of Ningxia Medical University, Ningxia Medical University, Yinchuan, 750004, China;bSurgery Laboratory, Institute of Medical Sciences, General Hospital of Ningxia Medical University, Ningxia Medical University, Yinchuan, 750004, China;cDept of Laboratory, Yinchuan Maternal And Child Health Care Hospital, Yinchuan, 750001, China;dDept of Obstetrics, General Hospital of Ningxia Medical University, Yinchuan, 750004, China;eDept of Gynecology, General Hospital of Ningxia Medical University, Yinchuan, 750004, China;fCollege of Pharmacy, Ningxia Medical University, Yinchuan, 750004, China ) - 出处: Chinese Pharmacological Bulletin 2025 Vol.41 No.12 P2268-2274
- 关键词: autophagy FRMD4A LC3B II/I p62 preeclampsia trophoblast cells
- 摘要: Aim To investigate the role of FRMD4A in autophagy of placental trophoblast cells in preeclampsia . Methods The placental tissues and clinical data of
- 作者:
李文霞 ,王晓晔 ,李志慧 ,黄丽娟 ,强克萍 ,赵启鹏 ,王艳华 ( 宁夏医科大学第一临床医学院.;宁夏医科大学总医院医学科学研究院外科学研究室;宁夏医科大学银川市妇幼保健院检验科;宁夏医科大学宁夏医科大学总医院产科.;宁夏医科大学总医院妇科.;宁夏医科大学药学院 ) - 出处: 中国药理学通报 2025 第12期
- 关键词: 子痫前期 滋养细胞 FRMD4A 自噬 LC3BⅡ/Ⅰ p62
- 摘要: 目的 探讨FRMD4A在子痫前期胎盘滋养细胞自噬中的作用。方法 获取正常妊娠和PE胎盘组织及临床资料,HE染色观察组织病理学变化;建立缺氧诱导的HTR-8/SVneo滋养细胞体外模型,Western blot分析胎盘组织及缺氧细胞模型中LC3BⅡ/Ⅰ及p62表达;qRT-PCR、Western bl
期刊
- 作者:
Wenbo Yan ,Hui Yuan ,Nuan Li ,Mei-Mei Zhang ,Dong Wang ,Luyao Dong ,Jiaxin He ,Nan Chao ,Yan Su ,Jian-Mei Gao ,Zhou Hong ,Yifan Ouyang ,Qi-Peng Zhao ,Yanru Fan ,Zu-Zhuang Wei ,Hua Chen ,Yu Huang ,Hao Yang ( 1School of Pharmacy, Ningxia Medical University, Yinchuan 750004, China;2These authors contributed equally.;3School of Basic Medicine, Ningxia Medical University, Yinchuan 750004, China;4College of Pharmaceutical Sciences and Cancer Center, Zhejiang University, Hangzhou 310058 Zhejiang, China;5Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Peking Union Medical College, No.1 Tiantan Xili, Dongcheng District, Beijing, 100050, China;6College of Life Science and Technology, Ningxia Polytechnic, Ningxia Open University, Yinchuan, 750021, China;7Fujian Key Laboratory of Toxicant and Drug Toxicology, School of Medicine, Ningde Normal University, Ningde, Fujian 352100, China;8College of Marine Sciences, Beibu Gulf University, Qinzhou, China ) - 出处: Dyes and Pigments 2026 Vol.246 Part 1 P113311
- 摘要: Cervical cancer, a leading malignancy in women, urgently requires novel therapeutic agents due to the lack of effective targets. This study reports YW
期刊
- 作者:
Nuan Li ,Hui Yuan ,Wenbo Yan ,Mei-Mei Zhang ,Jian-Mei Gao ,Nan Chao ,Jiaxin He ,Yifan Ouyang ,Zhou Hong ,Yanru Fan ,Zu Zhuang Wei ,Yu Huang ,Hao Yang ,Qi-Peng Zhao ( 1School of Pharmacy, Ningxia Medical University, Yinchuan 750004, China.;2These authors have contributed equally.;3School of Basic Medicine, Ningxia Medical University, Yinchuan 750004, China.;4Fujian Key Laboratory of Toxicant and Drug Toxicology, School of Medicine, Ningde Normal University, Ningde, Fujian 352100, China;5College of Life Science and Technology, Ningxia Polytechnic, Ningxia Open University, Yinchuan 750021, China;6College of Marine Sciences, Beibu Gulf University, Qinzhou, China ) - 出处: Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 2026 Vol.346 P126844
- 摘要: Mitochondrial G-quadruplexes have recently emerged as a highly promising therapeutic target in oncology. This is because the frequency of their forma
期刊
- 作者:
Zhang, Wenjin ,Cao, Zhe ,Xie, Zhicai ,Lang, Duoyong ,Zhou, Li ,Chu, Yuankui ,Zhao, Qipeng ,Zhang, Xinhui ,Zhao, Yunsheng ( 1College of Pharmacy, Ningxia Medical University, Yinchuan, 750004, PR China 2Laboratory Animal Center, Ningxia Medical University, Yinchuan, 750004, PR China 3Ningxia Engineering and Technology Research Center of Hui Medicine Modernization, Ningxia Collaborative Innovation Center of Hui Medicine, Laboratory of Hui Ethnic Medicine Modernization, Ministry of Education, Ningxia Medical University, Yinchuan, 750004, PR China 4College of Clinical Medicine of Ningxia Medical University/General Hospital of Ningxia Medical University, Yinchuan 750004, P. R. China *For correspondence ) - 出处: Scientia Horticulturae 2017 Vol.224 P280-285
- 关键词: Endogenous hormones Roots biomass Secondary metabolites Stellaria dichotoma L. var. lanceolata Bge Water stress
- 摘要: The experiment was carried out with plants grown in pots with soil to determine the effects of different levels of water stress on roots biomass, seco
期刊
- 作者:
Lili Bao ,Fangxia Qiao ,Na Yu ,Qipeng Zhao ,Wenbao Zuo ,Jianhong Yang ( 1Department of Pharmaceutics, School of Pharmacy, Ningxia Medical University, No.1160 Shengli South Street, Yinchuan 750004, PR China;2These authors contributed equally to this work.;3Department of Preparation Center, General Hospital of Ningxia Medical University, No.804 Shengli South Street, Yinchuan 750004, PR China;4Department of Pharmacology, School of Pharmacy, Ningxia Medical University, No. 1160 Shengli South Street, Yinchuan 750004, PR China ) - 出处: International Journal of Biological Macromolecules 2025 Vol.309 Part 4 P143028
- 摘要: Blepharitis is a common eyelid inflammation with irritation and discomfort, which can lead to meibomian gland dysfunction and dry eye. However, most
期刊
- 作者:
Lili Bao ,Fangxia Qiao ,Na Yu ,Qipeng Zhao ,Wenbao Zuo ,Jianhong Yang ( 1Department of Pharmaceutics, School of Pharmacy, Ningxia Medical University, No.1160 Shengli South Street, Yinchuan 750004, PR China;2These authors contributed equally to this work.;3Department of Preparation Center, General Hospital of Ningxia Medical University, No.804 Shengli South Street, Yinchuan 750004, PR China;4Department of Pharmacology, School of Pharmacy, Ningxia Medical University, No. 1160 Shengli South Street, Yinchuan 750004, PR China ) - 出处: International Journal of Biological Macromolecules 2025 P143028
- 摘要: Blepharitis is a common eyelid inflammation with irritation and discomfort, which can lead to meibomian gland dysfunction and dry eye. However, most
- 作者:
党燕宁 ,权洪峰 ,赵启鹏 ( 宁夏医科大学药学院 ) - 出处: 高校医学教学研究(电子版) 2024 第14卷 第5期 P57-62
- 关键词: 中药药理学 课程思政 思政元素
- 摘要: 中药药理学是中药学专业的必修课,其实验教学更是培养学生创新思维和科研能力等素养的有效途径。本文以国内高等院校开设的中药药理学实验课程为基础,总结归纳各高校中药药理学实验内容的异同点,并围绕中药药理学科任务、实验内容、药物作用特点、科研实践等方面,融入家国情怀和爱国精神教育、中医药文化自信教育、职业道
- 赵启鹏,男,民族,汉,1981年10月生于山东枣庄,中共党员,教授,硕士生导师。2010年毕业于成都中医药大学并获博士研究生学位,历任药学院教学办主任等职。现兼任中国民族医药协会科研分会常务理事等职务。获国家实用新型专利2项,自治区教学成果一等奖1项。出版专著1部、教材2部。发表论文十余篇,获宁夏自然科学优秀学术论文二等奖1项。