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期刊
- 作者:
Jiamei Yang ,Geng G. Tian ,Shangxiao Wei ,Han Gao ,Wenyue Zhang ,Chunlan Mu ,Rong Hu ,Jianqiang Yu ,Ji Wu ( 1School of Basic Medical Sciences, Key Laboratory of Fertility Preservation and Maintenance of Ministry of Education, Ningxia Medical University, Yinchuan 750004, China;2School of Pharmacy, Ningxia Medical University, Yinchuan 750004, China;3contributed equally to this work.;4Shanghai Key Laboratory of Veterinary Biotechnology, School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai 200240, China;5Key Laboratory for the Genetics of Developmental & Neuropsychiatric Disorders (Ministry of Education), Bio-X Institutes, Shanghai Jiao Tong University, Shanghai 200240, China;6Reproductive Medicine Center, General Hospital of Ningxia Medical University, Ningxia, China;7Institute of Medical Sciences, General Hospital of Ningxia Medical University, Ningxia, China ) - 出处: Metabolism and Diseases 2026 Vol.1 No.1 P100004
- 关键词: 24-epibrassinolide Female germline stem cell RIC-seq Gm26624-Abcg2 interaction NMT1
- 摘要: Background Recent studies indicate that approximately 15% of couples worldwide are affected by infertility. The discovery of female germline stem cell
期刊
- 作者:
Jiamei Yang ,Geng G. Tian ,Shangxiao Wei ,Han Gao ,Wenyue Zhang ,Chunlan Mu ,Rong Hu ,Jianqiang Yu ,Ji Wu ( 1School of Basic Medical Sciences, Key laboratory of Fertility Preservation and Maintenance of Ministry of Education, Ningxia Medical University, Yinchuan 750004, China;2School of Pharmacy, Ningxia Medical University, Yinchuan 750004, China;3contributed equally to this work.;4Shanghai Key Laboratory of Veterinary Biotechnology, School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai 200240, China;5Key Laboratory for the Genetics of Developmental & Neuropsychiatric Disorders (Ministry of Education), Bio-X Institutes, Shanghai Jiao Tong University, Shanghai 200240, China;6Reproductive Medicine Center, General Hospital of Ningxia Medical University, Ningxia, China;7Institute of Medical Sciences, General Hospital of Ningxia Medical University, Ningxia, China ) - 出处: Metabolism and Diseases 2026 P100004
- 关键词: 24-epibrassinolide Female germline stem cell RIC-seq Gm26624-Abcg2 interaction NMT1
- 摘要: Background Recent studies indicate that approximately 15% of couples worldwide are affected by infertility. The discovery of female germline stem cell
科技成果
- 作者:
刘丹 ,曹佳 ,胡蓉 ,裴秀英 ,梁雪云 ,王立斌 ,韩淑霞 ,马静文 ,杨志娟 ,雍圆圆 - 关键词: 补片 类器官 水凝胶 细胞 工程
- 摘要: 宫腔粘连是由于创伤后子宫内膜修复障碍、呈现瘢痕愈合的最后形式。育龄期为主要的患病年龄,由此导致的难治性不孕问题给社会、家庭、经济和心理健康带来巨大的负担。目前,传统的综合治疗生殖预后的改善仅为40%-50%。这种困境的实质是子宫内膜创伤后再生障碍,无法形成接纳受精卵种植的“土壤”。干细胞及再生医学的
- 作者:
刘丹 ,曹佳 ,胡蓉 ,裴秀英 ,梁雪云 ,王立斌 ,韩淑霞 ,马静文 ,杨志娟 ,雍圆圆 - 关键词: 细胞3D培养 子宫内膜干细胞 补片 宫腔粘连 难治性不孕
- 摘要: 宫腔粘连是由于创伤后子宫内膜修复障碍、呈现瘢痕愈合的最后形式。育龄期为主要的患病年龄,由此导致的难治性不孕问题给社会-家庭-经济-心理健康带来巨大的负担。目前,传统的综合治疗生殖预后改善仅为40%-50%。这种困境的实质是子宫内膜创伤后再生障碍,无法形成接纳受精卵种植的“土壤”。干细胞及再生医学的发
科技成果
- 作者:
刘丹 ,曹佳 ,胡蓉 ,裴秀英 ,梁雪云 ,王立斌 ,韩淑霞 ,马静文 ,杨志娟 ,雍圆圆 - 关键词: 子宫内膜干细胞 宫腔粘连 临床转化 自体 补片
- 摘要: 宫腔粘连是由于创伤后子宫内膜修复障碍、呈现瘢痕愈合的最后形式。育龄期为主要的患病年龄,由此导致的难治性不孕问题给社会-家庭-经济-心理健康带来巨大的负担。目前,传统的综合治疗生殖预后改善仅为40%-50%。这种困境的实质是子宫内膜创伤后再生障碍,无法形成接纳受精卵种植的“土壤”。干细胞及再生医学的发
期刊
- 作者:
Guiyi Ji ,Yunxing Fu ,Linlin Song ,Rong Hu ( 1Department of Reproductive Medicine, General Hospital of Ningxia Medical University, Yinchuan, Ningxia 750004, PR China;2The authors contributed equally to this work;3Department of Reproductive Medicine, West China Second Hospital, West China Women's and Children's Hospital, Sichuan University, Chengdu, Sichuan, PR China;4Department of Gynecology, General Hospital of Ningxia Medical University, Yinchuan, Ningixa 750004, PR China ) - 出处: Journal of Reproductive Immunology 2026 Vol.173 P104833
- 摘要: Female genital tuberculosis is a major cause of infertility in regions where it is common, causing permanent damage to the reproductive tract. It mai
- 作者:
Yuan Zhang ,Ruiping Lu ,Yulan Ma ,Jie Ma ,Linlin Song ,Fanqing Zhou ,Jingwen Guo ,Rong Hu ( 1Department of Gynecology, General Hospital of Ningxia Medical University, 750004, China;2Ningxia Medical University, Yinchuan, Ningxia, 750004, China;3Department of Prenatal Diagnosis Center, General Hospital of Ningxia Medical University, 750004, China;4Reproductive Medicine Center, General Hospital of Ningxia Medical University, Yinchuan, Ningxia, 750004, China;5Ningxia Key Laboratory of Clinical and Pathogenic Microbiology, Institute of Medical Sciences, General Hospital of Ningxia Medical University, Yinchuan, Ningxia, 750004, China;6Key Laboratory of Fertility Preservation and Maintenance of Ministry of Education, Ningxia Medical University, Yinchuan, Ningxia, 750004, China ) - 出处: Placenta 2025 Vol.169 P21-29
- 关键词: Autophagy Lysosome Placental development hyperhomocysteinemia.
- 摘要: Objective Hyperhomocysteinemia , characterized by elevated homocysteine levels, is associated with adverse pregnancy outcomes, though its mechanistic
- 作者:
Yuan Zhang ,Ruiping Lu ,Yulan Ma ,Jie Ma ,Linlin Song ,Fanqing Zhou ,Jingwen Guo ,Rong Hu ( 1Ningxia Medical University, Yinchuan, Ningxia 750004, China;2Department of Gynecology, General Hospital of Ningxia Medical University, 750004, China;3Department of Prenatal Diagnosis Center, General Hospital of Ningxia Medical University, 750004, China;4Reproductive Medicine Center, General Hospital of Ningxia Medical University, Yinchuan, Ningxia 750004, China;5Ningxia Key Laboratory of Clinical and Pathogenic Microbiology, Institute of Medical Sciences, General Hospital of Ningxia Medical University, Yinchuan, Ningxia 750004, China;6Key Laboratory of Fertility Preservation and Maintenance of Ministry of Education, Ningxia Medical University, Yinchuan, Ningxia, 750004, China ) - 出处: Placenta 2025
- 摘要: Objective Hyperhomocysteinemia , characterized by elevated homocysteine levels, is associated with adverse pregnancy outcomes, though its mechanistic
期刊
- 作者:
Fu, Yun-Xing ,Ji, Jing ,Shan, Fang ,Li, Jialing ,Hu, Rong ( 1 Ningxia Medical University, General Hospital of Ningxia Medical University, 750004, Yinchuan, Ningxia, China ;2 Reproductive Medicine Center, General Hospital of Ningxia Medical University, Key Laboratory of Fertility Preservation and Maintenance of Ministry of Education, Ningxia Medical University, 750004, Yinchuan, Ningxia, China ) - 出处: Stem Cell Research & Therapy 2021 Vol.12 No.1 P1-13
- 关键词: Mesenchymal stem cells Ovarian function Premature ovarian failure
- 摘要: Premature ovarian failure is one of the common disorders found in women leading to 1% female infertility. Clinical features of POF are hypoestrogenis
期刊
- 作者:
Chen, Ping ,Zhao, Xinyan ,Tian, Geng G. ,Yuan, Xiaoyan ,Li, Xinyue ,Li, Zezhong ,Yu, Xiaoli ,Hu, Rong ,Wang, Yanrong ,Pei, Xiuying ,Zhou, Huchen ,Wu, Ji ( 1 Key Laboratory of Fertility Preservation and Maintenance of Ministry of Education, Ningxia Medical University, Yinchuan, China ;2 Key Laboratory for the Genetics of Developmental & Neuropsychiatric Disorders (Ministry of Education), Bio-X Institutes, Shanghai Jiao Tong University, Shanghai, China ;3 State Key Laboratory of Microbial Metabolism, School of Pharmacy, JiaoTong University, Shanghai, China ;4 Reproductive Medicine Center, General Hospital of Ningxia Medical University, Yinchuan, Ningxia, China ) - 出处: Gene 2021 Vol.766
- 关键词: Autophagy C28 Epigenetics Female germline stem cells RNA-Seq
- 摘要: C28 can inhibit the proliferation and reduce cell viability of FGSCs in vitro by autophagy. • The changes of histone H3K27 acetylation involves in C28
- 胡蓉,女,回族,1974年02月生于宁夏,中共党员,教授,硕士生导师。2014年毕业于郑州大学并获博士学位,现任研究生管理办公室主任、生殖医学中心副主任等职,兼任中华医学会生殖医学分会全国委员、实验室学组委员,伦理与管理学组委员,医促会生殖医学分会全国委员,中国医师协会整合医学医师分会整合医学生殖医学专业委员会委员,《生殖与避孕》杂志编委等职务。国家“百千万人才工程”第三层次人选。获得首届宁夏科技创新争先奖、宁夏第十五届青年科技奖、宁夏回族自治区科技创新领军人才。主持国家自然科学基金项目2项,省部级项目8项。获宁夏回族自治区科技进步奖3项;参与制定我国辅助生殖技术规范。发表学术论文68篇。主编或副主编专著2部。