作者:
He, Bintao
,
Cheng, Yiran
,
Li, Hongjia
,
Gao, Xiang
,
Gao, Xin
,
Zhang, Fa
,
Han, Renmin
(
1Research Center for Mathematics and Interdisciplinary Sciences, Ministry of Education Frontiers Science Center for Nonlinear Expectations, Shandong University, Qingdao; 266237, China;2College of Medical Information and Engineering, Ningxia Medical University, Yinchuan; 750004, China;3School of Medical Technology, Beijing Institute of Technology, Beijing; 100081, China;4State Key Laboratory of Microbial Technology, Shandong University, Qingdao; 266237, China;5King Abdullah University of Science and Technology (KAUST), Computational Bioscience Research Center (CBRC), Computer, Electrical and Mathematical Sciences and Engineering (CEMSEDivision, Thuwal; 23955, Saudi Arabia
)
出处:
arXiv 2026
摘要:
Understanding protein flexibility and its dynamic interactions with other molecules is essential for studying protein function. Although cryogenic ele...
作者:
Xiaolan Luo
,
Cilin Zhao
,
Feifei Yu
,
Xiaoyan Dong
,
Yinju Hao
,
Huiping Zhang
,
Bin Liu
,
Yideng Jiang
(
1NHC Key Laboratory of Metabolic Cardiovascular Diseases Research, Ningxia Medical University, Yinchuan, 750004, China;2School of Inspection, Ningxia Medical University, Yinchuan, 750004, China;3These authors contributed equally to this work.;4Ningxia Key Laboratory of Vascular Injury and Repair Research, Yinchuan, 750004, China;5School of Basic Medical Sciences, Ningxia Medical University, Yinchuan, 750004, China;6Medical Experimental Center, General Hospital of Ningxia Medical University, Yinchuan, 750004, China;7Department of Medical Genetics, Hunan Provincial Maternal and Child Health Hospital, Changsha, 410008, China;8College of Biology, Hunan University, Changsha, 410082, China
)
出处:
Chemical Engineering Journal 2026
P176037
摘要:
Atherosclerosis is characterized by chronic, persistent inflammation and lipid deposition. Macrophage mitochondrial dysfunction leads to excessive re...
作者:
Jieyuan Du
,
Hao Yang
,
Fei Jin
,
Guoping Jiang
,
Zhiliang Jin
(
1School of Chemistry and Chemical Engineering, Ningxia Key Laboratory of Solar ChemicalConversion Technology, Key Laboratory for Chemical Engineering and Technology, State Ethnic Affairs Commission, North Minzu University, Yinchuan 750021, China;2Equal contribution.;3School of Basic Medical Science, Ningxia Medical University, Yinchuan 750004, China
)
出处:
Chemical Engineering Science 2026 Vol.331
P123996
摘要:
To address the fundamental limitation of insufficient light harvesting, the composite photocatalyst CM-10 was constructed by implementing strong elect...
作者:
Wenhui Jing
,
Sijin Xu
,
Cunbing Li
,
Yuxing Li
,
Xiaoyun Li
,
Hong Sui
,
Xueyan Fu
(
1School of Pharmacy, Ningxia Medical University, No. 1160, Shengli Street, Xingqing District, Yinchuan, Ningxia Province 750004, PR China;2Key Laboratory of Protection, Development and Utilization of Medicinal Resources in Liupanshan Area (Ningxia Medical University), Ministry of Education, PR China
)
摘要:
Thermal processing strongly influences the bioactivity of phytochemical-rich foods, but the mechanisms behind functional loss under different conditio...
作者:
Jianrong Na
,
Lei Huang
,
Lijuan Wang
,
Yue Ni
,
Yisheng Chen
,
Qiancheng Luo
,
Yan Li
(
1Department of Respiratory and Critical Care People's Hospital of Ningxia Hui Autonomous Region, Ningxia Medical University Medicine, Yinchuan 750001, China;2The Third Clinical Medical College of Ningxia Medical University, Yinchuan 750001, China;3Department of Molecular Cell and Cancer Biology, University of Massachusetts Chan Medical School, 55 Lake Avenue North, Worcester, MA 01605, USA;4Department of Endocrinology, General Hospital of Ningxia Medical University, 804 Shengli St, Xingqing District, Yinchuan 750001, China;5School of Gongli Hospital Medical Technology, University of Shanghai for Science and Technology, Yangpu District, Shanghai, 200093, China;6Fujian Key Laboratory of Toxicant and Drug Toxicology, Medical College, Ningde Normal University, Department of Vascular and Interventional Radiology, Ningde Municipal Hospital of Ningde Normal University, Ningde, China;7Fujian Key Laboratory of Medical Bioinformatics, Fujian Medical University, Fuzhou, China;8Department of Critical Care Medicine, Shanghai Pudong New Area Gongli Hospital, Shanghai, 200135, China;9School of Basic Medical Sciences, Ningxia Medical University, Ningxia, 750004, China
)
摘要:
Non-alcoholic fatty liver disease and cardiovascular disease frequently co-occur, driven by inter-organ metabolic crosstalk that current single-targ...
作者:
Hao Wang, Chunfang Li, Fangyuan Zhang, Benjamin Kersch-Hunt, Jordan E Gardiner, Lijuan Ren, Ying Li, Simon E Lewis, Yanling Mu, Qingqiang Yao, Luling Wu, Robin R Groleau, Wenhao Zhai, Zhen Liu, Tony D James, Eric V Anslyn, Kai Wang
(
Affiliations 1 State Key Laboratory of Advanced Drug Delivery and Release Systems, School of Pharmaceutical Sciences & Institute of Materia Medica, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan 250117, Shandong, People's Republic of China. wk-sandy@mail.nankai.edu.cn. 2 College of Medical Engineering, Jining Medical University, Jining 272067, Shandong, People's Republic of China. 3 Department of Chemistry, University of Bath, Bath, BA2 7AY, UK. t.d.james@bath.ac.uk. 4 Lifecare Chemistry, Bath, BA2 4BL, UK. 5 Lifecare Chemistry Laboratory, Science Creates, Bristol, BS2 0XJ, UK. 6 State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry, Nanjing University, 163 Xianlin Avenue, Nanjing 210023, People's Republic of China. zhenliu@nju.edu.cn. 7 Department of Life Sciences, University of Bath, Bath, BA2 7AY, UK. rg598@bath.ac.uk. 8 College of Pharmacy, Ningxia Medical University, Yinchuan 750004, Ningxia, People's Republic of China. 20220104@nxmu.edu.cn. 9 School of Chemistry and Chemical Engineering, Henan Normal University, Xinxiang 453007, People's Republic of China. 10 Department of Chemistry, University of Texas at Austin, Austin, Texas 78712, USA. anslyn@austin.utexas.edu.
)
出处:
Chemical Society reviews 2026
摘要:
Glucose and glucose homeostasis are central to the regulation of biological processes, and the development of probes for glucose sensing and imaging i...
作者:
Peng Chang, Kuoye Tian, Xiaoyu Yang, Dehong Chen, Chenying Wang, Ke Li, Dan Chen, Yangyang Feng, Yun Zeng, Yonghua Zhan, Wenhua Zhan
(
Affiliations 1 School of Life Science and Technology, Xidian University and Engineering Research Center of Molecular and Neuro Imaging, Ministry of Education, Xi'an, 710126, PR China. 2 Xi'an Key Laboratory for Prevention and Treatment of Common Aging Diseases, Translational and Research Centre for Prevention and Therapy of Chronic Disease, Institute of Basic and Translational Medicine, Xi'an Medical University, Xi'an, 710021, PR China. 3 Department of Radiation Oncology, General Hospital of Ningxia Medical University, Yinchuan, 750004, PR China. 4 School of Life Science and Technology, Xidian University and Engineering Research Center of Molecular and Neuro Imaging, Ministry of Education, Xi'an, 710126, PR China. yzeng@xidian.edu.cn. 5 School of Life Science and Technology, Xidian University and Engineering Research Center of Molecular and Neuro Imaging, Ministry of Education, Xi'an, 710126, PR China. yhzhan@xidian.edu.cn. 6 Department of Radiation Oncology, General Hospital of Ningxia Medical University, Yinchuan, 750004, PR China. zhanwhgood@163.com. 7 State Key Laboratory of Pathogenesis, Prevention and Treatment of High Incidence Diseases in Central Asia, Xinjiang Medical University, Urumqi, 830054, PR China. zhanwhgood@163.com.
)
出处:
Journal of nanobiotechnology 2026
关键词:
2-methoxyestradiol CTLA-4 Immunogenic cell death Ipilimumab Metabolic reprogramming.
摘要:
Immune checkpoint blockade therapy, represented by CTLA-4 inhibitors like ipilimumab, faces limited clinical efficacy due to tumor immune evasion and ...
作者:
Yaqin Cai
,
Li Peng
,
Yaping Mai
,
Jueshuo Guo
,
Qian Zhang
,
Haiyan Cai
,
Wenbao Zuo & …Jianhong Yang
(
1Department of Pharmacy, People’s Hospital of Ningxia Hui Autonomous Region, No.255 Zhengyuan North Street, Yinchuan, 750002, P.R. China;2School of Pharmacy, Ningxia Medical University, No.1160 Shengli South Street, Yinchuan, 750004, P. R. China;3Department of Pharmacy, General Hospital of Ningxia Medical University, No.804 Shengli South Street, Yinchuan, 750004, PR China;4Department of Science and Technology Center, Ningxia Medical University, No.1160 Shengli South Street, Yinchuan, 750004, PR China;5Department of Neurology, People’s Hospital of Ningxia Hui Autonomous Region, No.255 Zhengyuan North Street, Yinchuan, 750002, P.R. China
)
出处:
Advanced Composites and Hybrid Materials 2026 Vol.9 No.2
摘要:
Nanozymes represent a class of functional nanomaterials that exhibit catalytic or enzyme-like activities and imaging capabilities, making them potenti...
作者:
Yunlong Zhang, Mingliang Pan, Fei Ma, Changting He, Qin Gu, Yongli Wang, Zhou Pan, Huijuan Wang, Yan Yan, Xinting Fu, Yue Jia, Han Duan, Yanqiu Wu, Zihui Wei, Jiamei Wang, Bin Li, Yuhui Liao, Liying Zhan
(
Affiliations 1 Department of Critical Care Medicine & Department of Emergency, Renmin Hospital of Wuhan University, Wuhan, Hubei 430060, China. 2 School of Basic Medical Sciences, Ningxia Medical University, Yinchuan 750004, Ningxia China. 3 School of Inspection, Ningxia Medical University, Yinchuan, Ningxia 750004, China. 4 Institute for Engineering Medicine, Kunming Medical University, Kunming, Yunnan 650500, China. 5 Department of Microbiology, School of Public Health, Southern Medical University, Guangzhou, Guangdong 510515, China.
)
出处:
ACS applied materials & interfaces 2026
关键词:
alveolar macrophage gasdermin D pyroptosis sepsis-induced acute lung injury tetrahedral DNA nanostructure.
摘要:
Sepsis-induced acute lung injury is a critical complication of sepsis characterized by severe pulmonary edema, hyper-inflammatory responses, and high...
作者:
Bo Wen
,
Zhenyu An
,
Yuyu Wang
,
Xueying Yang
,
Xin Guo
,
Zhiliang Jin
(
1School of Chemistry and Chemical Engineering, Ningxia Key Laboratory of Solar Chemical Conversion Technology, North Minzu University, Key Laboratory for Chemical Engineering and Technology, State Ethnic Affairs Commission, Yinchuan, 750021, PR China;2College of Pharmacy, Ningxia Characteristic Traditional Chinese Medicine Modern Engineering Research Center, Ningxia Medical University, Yinchuan, 750021, PR China;3Analysis and Testing Center of Ningxia Hui Autonomous Region, North Minzu University, Yinchuan, 750021, PR China
)
出处:
International Journal of Hydrogen Energy 2026 Vol.229
P154656
摘要:
As environmental problems worsen and global energy demand continues to grow, photocatalytic hydrogen evolution technology is regarded as a promising g...